Topical Hydrators

Products that hydrate the skin play a variety of roles. Hydrators and occlusives work with the surface of the skin in a barrier function, sup- plying oils and hydration. Humectants and emollients work within the skin’s layers, attracting and holding water in the cells, depending on their ability to penetrate.

Hydrators impart a temporary barrier to damaged stratum corneum, which allows time for reparation of this layer. This enables surface hydration, treating dry skin that is not necessarily dehydrated. Hydrators of the new millennium include agents that mimic natural ingredients and functions, stimulating hydration and repairing the mantle.

Occlusives (also known as lipid barriers) physically block the surface of the stratum corneum and reduce transepidermal water loss. This increases the water content in the stratum corneum, producing a state of hydration. Occlusion is one of the best treatments for dry skin because 1) transepidermal water is the most effective source of water for the skin, and occlusives prevent excessive water loss, and 2) these occlusive agents have some emollient effect, as below.

Emollients fill the spaces between the corneocytes, the keratinized cells of the stratum corneum, providing therapeutic improvement to desquamation defects. Emollients smooth roughened skin, improve the skin’s appearance, and lubricate and replace natural skin lipids, providing some occlusion.

Humectants are substances that attract and provide water to the skin and then bind it to the cells of the epidermis and dermis. The source of the water for the epidermis is usually transepidermal, from the air and topical products. The source of hydration for the dermis is derived from the functional aspects of the layer, such as the blood and dermal production of glycosaminoglycans and other inherent components, and from topical products designed with sophisticated delivery systems.

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